现年20岁的福永美绪（井上真央 饰）是一个患有先心的开朗女孩，因身体原因，她从小得到周围人的宠爱和纵容，以致于养成了别扭固执的霸道性格。自从十年前父母离婚后，她一直跟随母亲在美国居住。眼看就要迎来了心脏手术的重要时刻，美绪得知手术只有五成的把握，于是决定在此之前返回日本，与多年未见的哥哥加纳和树（伊藤英明 饰）小聚一下。热爱摄影的和树此前曾以摄影师为目标全速奔走，但在某起事件后他变得浑浑噩噩，毫无进取之心。妹妹的意外到来自然令和树分外开心，从小感情就好的两兄妹重拾了断掉十年的记忆和情怀。由于西方文化和自身性格的原因，美绪渐渐让和树及其周围的人感到不安。 兄妹俩乐趣与感动并存的重逢，也正是影响各自命运的开始……A bitter-sweet and uplifting comedy drama about a young girl Mio and her brother Kazuki. To treat her illness overseas, Mio has been living away from her older brother Kazuki for the past ten years. After learning about the upcoming surgery, which she has only a fifty percent chance of survival, Mio decides to fly back to Japan to spend time with Kazuki. Looking forward to seeing his sweet younger sister, Kazuki anxiously awaits Mio's return in Japan. However, their reunion is nothing but full of surprises as Mio has transformed from the innocent sickly girl Kazuki remembers from ten years ago into a sassy woman with an attitude. Kazuki has difficulty dealing with his wickedly selfish younger sister, but soon learns about the truth of her medical condition and has a change of heart.
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