平凡的高中生须藤要,收到了一封从未听说过的App「达尔文游戏」发来的邮件。将App启动的要,被卷入了一场玩家之间驱使异能战斗的游戏。在不明就里的情形之下,面对袭来的强力玩家,要能否在与他们的对战中制胜,并活到最后呢!?An unknowing Sudou Kaname is invited to try out a new mysterious mobile app game called Darwin's Game, but later realizes that he's in for more than he's bargained for when he finds out that there's no way to quit the game.